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The European Medicines Agency began investigating 150 reports of self-harm and suicidal thoughts linked to these medications

In this trial, a combination approach led to 60% of participants reaching the target weight loss of 20% or more, and approximately one in four participants (23%) had a weight loss of 30% or more on the basis of the trial-product estimand (i.e., when participants were treated as intended), the study authors wrote in NEJM

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Approved by the FDA for chronic weight management, it works by mimicking a hormone that helps control blood sugar, suppress appetite, and increase feelings of fullness