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Natural compounds Natural compounds further highlight the therapeutic relevance of autophagy-mitophagy modulation
When glutathione neutralizes a free radical or a reactive oxygen species, it becomes oxidized and forms GSSG
Role for glutathione peroxidase-4 in brain development and neuronal apoptosis: Specific induction of enzyme expression in reactive astrocytes following brain injury
Furthermore, most studies relied on surrogate endpoints, such as albuminuria, without directly assessing renal function decline or definitive clinical events
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