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Presented for research literature review only Barton Duell P et al
Im just saying, lets be careful in select patients because I think theres the potential to do harm. You found hypotension was most common among patients over 65 and those with diabetes
Nat Rev Cardiol 23 , 449451 (2026)
Additionally, stress-inducing agents such as tunicamycin, thapsigargin and histidinol have been shown to modulate CHAC1 regulation, indicating its involvement not only during ER stress but also in the context of the ISR ( CHAC1 promoter is the primary mechanism for the transcriptional upregulation of the gene
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