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IBM Corporation, Armonk, New York, United States) reported that GLP-1RA was associated with a lower incident risk of prostate cancer [the adjusted odds ratio (aOR) 0.81], lung cancer (aOR 0.81), and colon cancer (aOR 0.85) and a higher incident risk of thyroid cancer (aOR 1.65) than metformin, and they also found similar association between these tumors and GLP-1RA in the FDA Adverse Event Reporting System (FAERS) database (Wang and Kim, 2022)
However, according to their prescription labels, phendimetrazine and phentermine are effective when compared to a placebo
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