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While our study highlights the significance of hepsin in the context of liver protection and its potential therapeutic implications in APAP-induced hepatotoxicity, there are limitations to consider when evaluating hepsin as a candidate drug or therapeutic strategy
Most documented protocols treat glutathione supplementation as a maintenance intervention rather than a cycled compound
Furthermore, this improvement was not permanent and, after six months of administration, only one (6.2%) participant continued to experience skin tone reduction
Pfundstein et al
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