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This triggers insulin release when blood sugar rises, reduces glucagon secretion from the liver, slows digestion to prevent post-meal sugar spikes, and helps you feel fuller for longer

Other pharmacotherapies not based on entero-pancreatic hormones Several therapies that are not based on entero-pancreatic hormones are currently under evaluation for obesity and they represent further therapeutic options, considering their distinct mechanism of WL to the entero-pancreatic hormone therapies

When you don't get enough, you're not just tired from eating less

These include glucagon-like peptide-1 (GLP-1) receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodium-glucose cotransporter-2 (SGLT-2) inhibitors