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While Mounjaro acts on both GIP and GLP-1 receptors, Ozempic acts solely on GLP-1 receptors
Additional areas of investigation Researchers are also studying semaglutide in obstructive sleep apnea (where weight loss significantly improves symptoms), heart failure with preserved ejection fraction (HFpEF), peripheral artery disease, polycystic ovary syndrome, and even addiction disorders
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Glucagon-like peptide-1 (GLP-1) medications may be used to treat type 2 diabetes, obesity, obstructive sleep apnea, and cardiovascular conditions, but Medicare Part D plans have historically not covered drugs for obesity due to federal exclusions
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