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Conclusions: SGLT2i and GLP-1RA were associated with improved survival, cardiovascular, and kidney outcomes with a favorable safety profile
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Furthermore, GIPR antagonism in combination with GLP-1R agonism synergistically reduced BW in DIO mice and obese cynomolgus monkeys 33 , suggesting the potential for a GIPR/GLP-1R bispecific molecule for improving the efficacy of obesity treatment
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