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4.5 Macrophages Macrophages sense HBV infection mainly through pattern recognition receptors (PRRs) such as TLR4, TLR2, and other DNA sensors like cGAS-STING that detect viral components, HBV DNA, HBsAg, and core proteins (80)

The bruises we are focusing on here occur as a result of traumatic injury with a sharp needle to the blood vessels near the surface of your skin