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Clinical research shows that glutathione: Inhibits melanin synthesis (the skin pigment responsible for dark spots) Gently fades marks without harsh side effects A recent industry study found that up to 82% of participants noticed reduced hyperpigmentation after using a glutathione cleanser for 8 weeks
Sometimes this issue is fixed simply by optimizing buffers, for instance by increasing salt or detergent concentration, so that the interacting protein no longer binds to the GST only control, but still binds to your GST-fusion protein of interest
Of course, there's still a lot to figure out
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