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Starting with a lower dose and then increasing it gradually helps to reduce the side effects that you experience, by allowing your body to adjust to the medication over time
Introduction Gut enteroendocrine cells (EECs) are specialized secretory cells that are sparsely scattered throughout the mucosal epithelium of the gastrointestinal (GI) tract and which constitute the largest endocrine organ by mass in the body ( Serotonin Serotonin (5-HT) is produced by enterochromaffin (EC) cells, which constitute ~50% of the total EEC population and are scattered throughout the length of the gut, from the stomach to the distal colon ( Although traditionally regarded as a regulator for gastric motility (32)
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These doses sit well within the range tested in animal safety studies and far below levels where any toxicity was observed
