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doi: 10.3390/ijms23052717 Summary Keywords peripheral serotonin, L-carnitine, fatigue, hypothyroidism, chronic fatigue syndrome (CFS), myalgic encephalomyelitis (ME), systemic exertion intolerance disease (SEID), mitochondria Citation Raij T and Raij K (2024) Association between fatigue, peripheral serotonin, and L-carnitine in hypothyroidism and in chronic fatigue syndrome
Reported outcomes may be dependent on some dosage and study conditions
A 2015 review in the Journal of Clinical Endocrinology confirming that GHRH analogs combined with ghrelin-pathway agonists produce a synergistic GH secretory response that exceeds additive effects when either compound is used alone provides the mechanistic basis for why combination therapy is the standard in supervised clinical settings
Infection represents the most serious risk
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