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Pharmacological activation of GPX4 ameliorates doxorubicin-induced cardiomyopathy

Reduction in Oxidized LDL-Cholesterol: The first column shows that individuals taking ME-3 had a 16% reduction in the levels of oxidized LDL-cholesterol compared to placebo controls.45 2

In the same work, cystine availability was lower in autochthonous PDAC tumours compared with subcutaneous tumours, supporting the relevance of anatomical location for the metabolic microenvironment

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