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Several limitations exist with oral semaglutide: Absorption challenges: Must be taken on an empty stomach with minimal water, and you cannot eat or drink anything else for 30-60 minutes afterward, which can be inconvenient for many patients
This is thus additional circumstantial evidence that while vitamin B 12 deficiency is strongly associated with vegetarianism, neither is likely to be the major reason for the increased incidence of diabetes
S.et al (2011)
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