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Compared to younger individuals, this vitamin deficiency is more common in older adults because of the higher prevalence of food-bound vitamin B 12 malabsorption (atrophic gastritis) and the higher incidence of the autoimmune condition, pernicious anemia (39)
Additionally, the administration of oral GLP-1 drugs requires strict guidance: for example, semaglutide must be taken on an empty stomach in the morning, with no more than 120 mL of water, and patients must wait at least 30 minutes before having breakfast
Involvement of melatonin
Consistent timing keeps signals tidy
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