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Yes, though a moderate interaction exists
Anche in questo caso gli studi parlano chiaro: il Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity, pubblicato sul The New England Journal of Medicine, dimostra che questo farmaco porta a una riduzione del peso del 13% nei pazienti a 6 mesi dallinizio della terapia, contro il 2 % del placebo, per arrivare al 15% circa a nove mesi
Sixth, the current estimates for NNT show large uncertainty, as seen with wide confidence intervals in some of the NNT results
However, in Sprague Dawley rats, GLP-1 monotherapy significantly increased kaolin intake compared with vehicle-treated rats and rats treated with MK-801 (Extended Data Fig
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