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These therapies improve glycemic control and aid in weight management, offering a less invasive alternative to injectable GLP-1 treatments while enhancing patient convenience and compliance
Oral semaglutide requires precise timing (empty stomach, 30 minutes before food) to ensure absorption, while injections bypass digestion entirely
This shift in behavior often results in gradual, sustained weight loss without the sense of restriction or deprivation that many diets bring
Since semaglutide does not affect CYP2C19 activity, it does not worsen this pharmacogenomic effect
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