FIGURE 5 Berberine activated GLP-1/GLP-1R/PKA signaling pathway in STC-1 cell STC-1 cell has many characteristics of natural intestinal endocrine cells, and can express and secrete many intestinal hormones such as GLP-1 (McCarthy et al., 2015)
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Convenience, ease of administration, comorbidities and concomitant medications all need to be taken into account when selecting the most appropriate GLP-1 RA [6], as well as efficacy