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Human clinical trials have primarily focused on skin rejuvenation rather than hair growth specifically, though the mechanisms overlap significantly
doi: 10.1016/j.beem.2023.101759 93 SorianoANesherGShoenfeldY
Afonina IS, Zhong Z, Karin M, Beyaert R
Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007
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