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They should also be instructed about signs and symptoms that warrant dose adjustment or medical evaluation, including severe gastrointestinal side effects or other unusual symptoms that may indicate adverse reactions, as determined relevant by the prescribing clinician
For reference, the rate of discontinuation in the semaglutide study referenced above was 4.5% around half the rate of orforglipron with a longer trial period
Articles like how much bacteriostatic water to add to peptides provide more details on proper reconstitution practices
British Journal of Haematology
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