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Studies have shown that cisplatin induces CAFs to secrete chemokine (CC motif) ligand 5 (CCL5), which inhibits cisplatin-induced tumor cell apoptosis by regulating the STAT3 and PI3K/Akt signaling pathways, thereby further promoting tumor cell resistance to cisplatin treatment [42]
Mol Cell 63:2133 Kaganovich D (2017) There is an inclusion for that: material properties of protein granules provide a platform for building diverse cellular functions
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