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We studied VPA toxicokinetics using a nonlinear mixed-effects model-based population approach and modeled individual plasma VPA/blood lactate concentration relationships
C.SilhavyT
de Graaf C, Donnelly D, Wootten D, Lau J, Sexton PM, Miller LJ, et al
La lgica es la siguiente: sin proteccin de patentes, ninguna empresa invertira miles de millones en investigacin si otra compaa pudiera copiar el medicamento inmediatamente sin haber asumido el riesgo econmico
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