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Medscape Dermatology

The narrow surgical margin used (smaller than the standard of care of 5 mm), combined with the limitation of the standard bread loafing technique of fixed tissue histology - result in a high "false negative" error rate, and frequent recurrences

As most of these disease states are degenerative in nature and lack curative therapy, the introduction of new and effective treatment options could provide patients and family members with hope, encouragement, and improved quality of life

The persistence of fatigue often correlates with the severity of gastrointestinal side effects, which tend to diminish as tolerance develops