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Various, NEJM & The Lancet Ready for longevity

IMP-366 induces necroptosis by FSP1 migration into the nucleus in a ferroptosis-dependent manner We established that IMP-366 facilitates FSP1 migration from the membrane to the nucleus and induces necroptosis in erastin-treated cells

Nummular oval macules with hyperpigmentation and mild desquamation at the junction of the nasolabial fold and the supralabial area bilaterally Figure 2