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Trials of tirzepatide in obesity and type 2 diabetes have shown improvements in blood pressure, cholesterol, and HbA1c (a marker of blood sugar control) alongside weight loss, though the SURMOUNT-MMO data will be the clearest evidence on cardiovascular outcomes
HbA1c reduced by -1.2%
How They Work Amplify Physiologic GH Pulses Each peptide increases pituitary output rather than supplying exogenous hormone, maintaining feedback controls and minimizing long-term shutdown
Integrative Medicine: A Clinician's Journal, 13 (1), 8
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