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wound-study protocols may exclude sensitivity to copper, peptides, excipients, adhesives, or dressings
A significant change in pH affects the structure of all macromolecules, for instance, presence of a higher proportion of H + or low pH solution cleaves DNA double helix strands by protonating the DNA phosphodiester groups and consequently destabilizing the hydrogen bonds linking DNA nitrogenous bases guanine and cytosine (G-C) ( E
The mature BDNF protein preferentially binds to TrkB, while proBDNF has a higher affinity for a different receptor called p75NTR
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