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This maybe a result of our analysis being from only a single stage (mid-L4) or because only a small number of cells are expressing the target gene under LIN-12 or GLP-1 control, resulting in only a small amount of total LAG-1 bound DNA, which is below the limit of detection in the ChIP-seq assay
"Several medullary nuclei displayed expression in only one sex, which opens entirely new questions about how GLP-1 circuits operate differently in the female and male brain." Several medullary nuclei displayed what the authors call sex-biased expression
Conformational changes in tyrosine 11 of neurotensin are required to activate the neurotensin receptor 1
What are the tolerability profiles of each
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