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Like other incretin-based therapies, retatrutide may slow gastric emptying, which could theoretically affect the absorption rate of orally administered medicines

An exceptionally low initiation rate was observed even in this potentially advantaged population suggests GLP-1 RA initiation rates in the broader Polish population may be equally concerning, if not worse

It may also be related to eating significantly less, dehydration, changes in blood sugar, nausea, or the body adjusting to a new routine

Some patients find that maintaining their goal weight for 6-12 months allows skin remodelling to occur, improving appearance over time