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First, as a copper-delivery carrier, the peptide shuttles copper between extracellular and intracellular compartments, modulating local availability of the metal for metalloenzymes including superoxide dismutase, cytochrome c oxidase, and lysyl oxidase

Institutional Accounts for Academic and Clinical Labs Account workflows are set up for universities, hospital research foundations, and CROs that need PO-driven ordering, net-30 invoicing, and a named procurement contact at Koi

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They participate in oxidative damage, regulate TJ modification, and activate inflammatory factors, and thus play a crucial role in the various mechanisms of BBB damage, including the kinin system, excitatory toxicity from toxic glutamate efflux, neutrophil recruitment, mitochondrial changes, and macrophage/microglial activation [106, 107]