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Description

10.1093/cvr/cvy304 127

Several drugs are currently in advanced clinical trials: Phase III Clinical Trials: IBI362 (Innovent/Eli Lilly), CagriSema (Novo Nordisk), Retatrutide (Eli Lilly), and Survodutide (Boehringer Ingelheim)

The primary outcome was the effect of GABA on OGTT, and the secondary exploratory outcomes included continuous glucose monitoring (CGM), cardiovascular indices and sleep quality

Many patients remain on it for multiple years, but periodic reevaluation is essential to assess ongoing benefit, side effects, and need for adjustment

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