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63,64 Accordingly, N1 neutrophils are typically characterized by a coordinated effector program that includes enhanced ROS generation, increased NETs formation, and elevated production of proinflammatory cytokines, together with transcriptional signatures enriched for chemokines, costimulatory and adhesion molecules
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They generally interact with key glands: the hypothalamus, pituitary, thyroid, adrenals, ovaries, and testes either through direct binding or through influencing upstream signals
*Correspondence: Xuebo Liu, [email protected] Chen, [email protected] This article was submitted to Atherosclerosis and Vascular Medicine, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
