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Given the implication of dopamine dysregulation and dopamine transporter in ADHD, we are curious about whether the D2R-DAT protein complex will prove to be a viable therapeutic target for ADHD

Instead, research points to activity across multiple interconnected systems, including modulation of the nitric oxide (NO) system, upregulation of growth factor expression (notably VEGF, EGF, and FGF pathways), promotion of angiogenesis, and activation of the FAK-paxillin signalling pathway involved in cell migration and tissue organisation

doi: 10.1111/dom.13816 37 MarreroDGHilliardMEMaahsDMMcAuliffe-FogartyAHHunterCM

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