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Tirzepatide works as a dual GLP-1 and GIP receptor agonist, enhancing appetite suppression, improving insulin sensitivity, and promoting earlier satiety
GLP-1 receptor activation slows gastric emptying, which reduces the rate of postprandial glucose absorption and attenuates the postprandial glucose excursion an effect that becomes measurable within the first weeks of the escalation phase even at the 2mg starting dose
The number of remaining bacteria was determined with a standard bacteria counting assay
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