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We further removed the GSA linker residues and found that a single GSA with two additional EF residues from the Eco RI cloning site is sufficient to activate the C347K mutant receptor at 30% of the activity of full-length peptide fusion receptor (Figure 5c, expression levels shown in Supplementary Figure S2A)
Synthesizing these correctly requires specialized equipment and expertise that not every peptide manufacturer possesses
10.1096/fasebj.31.1_supplement.993.3Abstract retrieved fromExperimental Biology 2017 Meeting 68 KrivicA.AnicT.SeiwerthS.HuljevD.SikiricP
Any switch should happen under medical supervision with a clear dosing plan
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