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Significantly more women reported moderate or high sexual desire following bremelanotide vs placebo (p = 0.0114), and among women attempting intercourse within 24 hours of treatment, significantly more reported satisfaction with their level of sexual arousal following bremelanotide vs placebo (p = 0.0256) providing the foundational female sexual dysfunction dataset that directed PT-141 toward HSDD clinical development

Existem situaes em que a contraindicao praticamente absoluta: Quimioterapia com nuseas e vmitos: os agonistas GLP-1 podem intensificar esses sintomas j frequentes com esquemas como FOLFOX, FOLFIRINOX, carboplatina/paclitaxel tornando o tratamento ainda mais difcil de tolerar e aumentando o risco de desidratao e internaes por toxicidade

doi:10.1016/S0307-4412(97)00167-2

PMC 6145203