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Kim, D., Paggi, J
In vivo murine MTB challenge experiments confirmed the protective efficacy conferred by metE when formulated as recombinant protein with AS01 or AddaS03 adjuvants, compared to the nave group
Endothelial cells can upregulate the expression of adhesion molecules and secrete inflammatory chemokines to bind and recruit immune cells, respectively, and inflammatory signals increase endothelial permeability to allow for immune infiltration to neighboring tissues [75]
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