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The landmark drug gained Food and Drug Administration (FDA) approval in 2005 under the brand name Byetta

Knowing how to manage them can help you stay comfortable and adherent to treatment: For nausea and digestive discomfort: Eat smaller, more frequent meals Limit ultra-processed foods and takeaways Stay well hydrated (2-3 litres a day) Consider ginger tea or supplements (shown to help in clinical settings) Avoid lying down immediately after eating For fatigue: Ensure adequate protein intake Maintain electrolyte balance by eating a diet based on whole foods (supplements not necessary unless prescribed) Prioritise 7-8 hours of sleep Consider timing your injection before bed if daytime fatigue is significant In clinical trials, approximately 65% of participants experienced at least one side effect during the first month, but this dropped significantly by month three as the body adjusted 1

Patients typically start with a lower dose of Wegovy, which is gradually increased over 16-20 weeks to minimize potential side effects such as nausea, vomiting, and diarrhea

Leave-one-out sensitivity analyses confirmed the direction and magnitude of the AUD finding but highlighted the limited evidence base for hospitalization