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Clinical Update 4/27/2026 Can SAMe Boost Depression Treatment

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Authors declare no competing non-financial interests

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Proglucagon, a precursor to both glucagon and GLP-1 is synthesized in alpha-cells of the pancreas, intestinal L-cells, and specific neurons in the hindbrain

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This is an important distinction from stimulant thermogenics, which force a rapid spike in norepinephrine and adrenaline output

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