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Marinho HS, Real C, Cyrne L, Soares H, Antunes F

An initial decline in eGFR is common after treatment initiation but typically stabilizes over time, contributing to long-term preservation of kidney function [108]

Bioinformatics analyses using the Broad Institute Connectivity Map identified GHK-Cu as a modulator of more than 4,000 human genes, with the expression signature appearing to reverse patterns associated with aging and age-related disease (PMID: 25904764)