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The STEP 1 clinical trial demonstrated average weight loss of approximately 15% of body weight over 68 weeks with semaglutide 2.4mg, but these results were achieved in conjunction with dietary counselling and a 500 kcal per day calorie deficit, as highlighted in NICE TA875
The difficulty of GLP-1 receptor agonist oral products is that GLP-1 is easily degraded by enzymes in the gastrointestinal tract
The scientists tracked various health metrics from the participants including heart rate and blood pressure
They feel better energetically, you know, their dry skin, hair loss, all these things start to improve
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