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Platelet Delivery System: T4 is ubiquitously expressed in cells and extracellular fluids, is released by platelets upon activation, and its concentration increases at sites of injury a distribution pattern that delivers the peptide directly into forming wounds (PMID 22944663)
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The classes that cannot be differentiated using these signatures are GSTLs and GHRs which usually exhibit VP and ES motives, and DHARs and mPGES-2 which have VP and DS motives
Luo M, He H, Kelley MR, Georgiadis MM
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