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Ingredient quality and transparency are top priorities, and we favored NAD+ supplements made in GMP-certified facilities, with third-party testing, and free of unnecessary additives
Sourcing is the biggest practical risk: purity and potency vary widely in the gray market
No long-term trials have evaluated continuous use, so the on/off pattern is a convention rather than a desensitization-validated requirement
Common side effects Microdosing typically produces a quieter side-effect profile than standard GLP-1 dosing
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