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Tan X et al
Both short- and long-acting GLP-1RAs such as exenatide, lixisenatide and liraglutide were shown to effectively cross the bloodbrain barrier (BBB) [39,40,41]
Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus
However, its worth noting that this study used intravenous deliverynot an oral supplementin a very specific clinical context, so its difficult to generalize these results to everyday use or weight loss
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