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In particular, poly-amidoamine (PAMAM) dendrimers were found to cross the BBB in animal models [10] and very recently it was demonstrated their ability to cross the BBB when complexed with long non-coding RNAs [11]
-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo
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The regulatory status of peptide therapies is actively evolving
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