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GLP-1s have exploded in popularity, to the where, according to the Kaiser Family Foundation, 12% of adults has taken Ozempic or another GLP-1 drug
This is especially true for those who are severely deficient
The peptide activates the VEGFR2-Akt-eNOS signaling cascade, leading to increased vascular endothelial growth factor (VEGF) expression and subsequent vessel development
Given the small absolute event rates, VTE considerations are unlikely to be a primary driver of treatment selection, but may provide reassurance regarding safety in patients at elevated thrombotic risk
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