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These nutrients work best when they maintain a steady level in your bloodstream and tissues

The white boxes indicate substrate values (M) and the blue boxes indicate velocities (M/hr)

Of these trials, four compared DPP-4 inhibitors against placebo (SAVOR-TIMI 53, EXAMINE, TECOS, CARMELINA), eight compared GLP-1RA against placebo (ELIXA, LEADER, SUSTAIN-6, EXSCEL, HARMONY, REWIND, PIONEER 6, AMPLITUTE-O) and eleven compared SGLT-2 inhibitors against placebo (EMPA-REG, CANVAS, DECLARE, CREDENCE, DAPA-HF, DAPA CKD, VERTIS-CV, EMPEROR-R, SCORED, SOLOIST-WHF, EMPEROR-P)

and (b) somatic HAMD symptoms as the sum of somatic anxiety + GIS anxiety + genitourinary anxiety + hypochondriasis