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The plausible main reason for -cell protective effects of GSH differing from other antioxidant effects is that GSH has multiple functions, such as maintaining levels of reduced glutaredoxin and glutathione peroxidase 35 and maintaining exogenous antioxidants such as vitamins C and E in their reduced (active) forms 36,37,38
Another bonus is muscle protection
Semax is a synthetic peptide derived from ACTH that enhances cognition and protects the brain without hormonal effects
Similarly, T-helper cell 17 skewing condition (TGF-, IL-23, IL-6, IL-1, and IL-21) also results in increased DPP-4 expression [34]
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