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These translational findings are an outgrowth of a mechanistic model in rodents with impaired plasticity of key brain areas relevant to mood, cognitive and other main disorders, wherein LAC levels are markedly decreased and signal abnormal brain and systemic functions
doi: 10.2337/diabetes.53.suppl_3.s26 43 SantilliFSimeonePGGuagnanoMTLeoMMaccaroneMTDi CastelnuovoAet al
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Albuminuria is independently associated with cardiac remodeling, abnormal right and left ventricular function, and worse outcomes in heart failure with preserved ejection fraction
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