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J Nutr 131:23822387 Pereira M, Jeyabalan J, Jorgensen CS, Hopkinson M, Al-Jazzar A, Roux JP, Chavassieux P, Orriss IR, Cleasby ME, Chenu C (2015) Chronic administration of glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice

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You can point out that in Canada, over 30% of the adult population has a BMI over 30 and a significant percentage will have BMIs greater than 27 and with weight responsive medical conditions