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In the realm of targeted therapy, the intermittent use of the PI3K// inhibitor BAY1082439 (NCT01728311) was shown to reprogram the immune microenvironment and sustain antitumor responses, particularly in PTEN-deficient cancers

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Trimetazidine pretreatment inhibits myocardial apoptosis and improves cardiac function in a Swine model of coronary microembolization

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